Clinical immunology Recombinant human interleukin receptor antagonist influences serum chemokines in patients with rheumatoid arthritis
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چکیده
منابع مشابه
Recombinant human interleukin receptor antagonist influences serum chemokines in patients with rheumatoid arthritis
OBJECTIVE To investigate the serum expressions of chemokines CCL2 and CCL3 in patients with rheumatoid arthritis (RA) who were treated with recombinant human interleukin 1 (IL-1) receptor antagonist (IL-1Ra). MATERIAL AND METHODS Serum CCL2 and CCL3 were determined using an enzyme-linked immunosorbent assay in 54 active RA patients before and after treatment with IL-1Ra or a placebo, as well ...
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BACKGROUND & OBJECTIVES Interleukin-1 receptor antagonist (IL-1Ra) is a naturally occurring anti-inflammatory molecule that blocks action of IL-1. Polymorphism in IL-1Ra gene intron 2 results in differences in production of IL-1Ra. These polymorphisms are reportedly associated with autoimmune disease susceptibility in different studies. However, such data are lacking from India. We undertook th...
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ژورنال
عنوان ژورنال: Central European Journal of Immunology
سال: 2014
ISSN: 1426-3912
DOI: 10.5114/ceji.2014.43717